5EAG

Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor Prochloraz

Summary for 5EAG

Entry DOI	10.2210/pdb5eag/pdb
Related	4WMZ 5EAB 5EAC 5EAD 5EAE 5EAF 5EAH
Descriptor	Lanosterol 14-alpha demethylase, Prochloraz, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	cyp51, prochloraz, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase-oxidoreducatse inhibitor complex, oxidoreductase/oxidoreducatse inhibitor
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	1
Total formula weight	62878.37
Authors	Tyndall, J.D.A.,Sabherwal, M.,Sagatova, A.A.,Keniya, M.V.,Wilson, R.K.,Woods, M.V.,Monk, B.C. (deposition date: 2015-10-16, release date: 2016-02-10, Last modification date: 2023-09-27)
Primary citation	Tyndall, J.D.,Sabherwal, M.,Sagatova, A.A.,Keniya, M.V.,Negroni, J.,Wilson, R.K.,Woods, M.A.,Tietjen, K.,Monk, B.C. Structural and Functional Elucidation of Yeast Lanosterol 14 alpha-Demethylase in Complex with Agrochemical Antifungals. PLoS ONE, 11:e0167485-e0167485, 2016 Cited by PubMed: 27907120 DOI: 10.1371/journal.pone.0167485 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation