5EA0

Structure of the antibody 7968 with human complement factor H-derived peptide

Summary for 5EA0

Entry DOI	10.2210/pdb5ea0/pdb
Descriptor	Heavy chain of antibody 7968 Fab fragment, Light chain of antibody 7968 Fab fragment, Complement factor H-related protein 2, ... (4 entities in total)
Functional Keywords	complement factor h cfh scr19 scr19-20, immune system
Biological source	Homo sapiens More
Cellular location	Secreted: P36980
Total number of polymer chains	3
Total formula weight	49355.16
Authors	Bushey, R.T.,Moody, M.A.,Nicely, N.I.,Alam, S.M.,Haynes, B.F.,Winkler, M.T.,Gottlin, E.B.,Campa, M.J.,Liao, H.-X.,Patz Jr., E.F. (deposition date: 2015-10-15, release date: 2016-05-25, Last modification date: 2023-09-27)
Primary citation	Bushey, R.T.,Moody, M.A.,Nicely, N.L.,Haynes, B.F.,Alam, S.M.,Keir, S.T.,Bentley, R.C.,Roy Choudhury, K.,Gottlin, E.B.,Campa, M.J.,Liao, H.X.,Patz, E.F. A Therapeutic Antibody for Cancer, Derived from Single Human B Cells. Cell Rep, 15:1505-1513, 2016 Cited by PubMed: 27160908 DOI: 10.1016/j.celrep.2016.04.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation