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5E8M

Crystal structure of human heparanase

Summary for 5E8M
Entry DOI10.2210/pdb5e8m/pdb
DescriptorHeparanase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsglycoside hydrolase, apo, protein, sugar, hydrolase
Biological sourceHomo sapiens (Human)
More
Cellular locationLysosome membrane; Peripheral membrane protein: Q9Y251 Q9Y251
Total number of polymer chains2
Total formula weight54565.65
Authors
Wu, L.,Davies, G.J. (deposition date: 2015-10-14, release date: 2015-11-18, Last modification date: 2020-07-29)
Primary citationWu, L.,Viola, C.M.,Brzozowski, A.M.,Davies, G.J.
Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22:1016-1022, 2015
Cited by
PubMed: 26575439
DOI: 10.1038/nsmb.3136
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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