Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5E7M

Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMPPNP

Summary for 5E7M
Entry DOI10.2210/pdb5e7m/pdb
Related5E7I 5E7J
DescriptorATP-dependent RNA helicase DDX3X, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
Functional Keywordsdead-box protein, rna helicase, reca fold, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus speckle: O00571
Total number of polymer chains1
Total formula weight51598.20
Authors
Floor, S.N.,Condon, K.J.,Doudna, J.A. (deposition date: 2015-10-12, release date: 2015-12-02, Last modification date: 2024-03-06)
Primary citationFloor, S.N.,Condon, K.J.,Sharma, D.,Jankowsky, E.,Doudna, J.A.
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.
J.Biol.Chem., 291:2412-2421, 2016
Cited by
PubMed: 26598523
DOI: 10.1074/jbc.M115.700625
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.304 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon