5E6V

Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit

Summary for 5E6V

Entry DOI	10.2210/pdb5e6v/pdb
Descriptor	Integrin beta-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	lymphocyte function-associated antigen-1, lfa-1, cell adhesion
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	25968.20
Authors	Sen, M.,Springer, T.A. (deposition date: 2015-10-10, release date: 2016-03-02, Last modification date: 2020-07-29)
Primary citation	Sen, M.,Springer, T.A. Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops. Proc.Natl.Acad.Sci.USA, 113:2940-2945, 2016 Cited by PubMed: 26936951 DOI: 10.1073/pnas.1601379113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation