5E5M

Crystal structure of mouse CTLA-4 in complex with nanobody

Summary for 5E5M

Entry DOI	10.2210/pdb5e5m/pdb
Related	5E03 5E56
Descriptor	Cytotoxic T-lymphocyte protein 4, CTLA-4 nanobody, GLYCEROL, ... (4 entities in total)
Functional Keywords	treatment of metastatic melanomas, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	8
Total formula weight	106542.46
Authors	Fedorov, A.A.,Fedorov, E.V.,Samanta, D.,Bonanno, J.B.,Almo, S.C. (deposition date: 2015-10-08, release date: 2016-10-12, Last modification date: 2019-01-30)
Primary citation	Fedorov, A.A.,Fedorov, E.V.,Samanta, D.,Bonanno, J.B.,Almo, S.C. Crystal structure of mouse CTLA-4 in complex with nanobody To Be Published,
Experimental method	X-RAY DIFFRACTION (2.182 Å)

Structure validation