5E58

Crystal Structure Of Cytochrome P450 2B35 from Desert Woodrat Neotoma Lepida in complex with 4-(4-chlorophenyl)imidazole

Summary for 5E58

Entry DOI	10.2210/pdb5e58/pdb
Related PRD ID	PRD_900003
Descriptor	Cytochrome P450 family 2 subfamily B, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
Functional Keywords	cytochrome p450; cyp2b35; neotoma lepida; woodrat, oxidoreductase
Biological source	Neotoma lepida (Desert woodrat)
Total number of polymer chains	6
Total formula weight	344157.37
Authors	Shah, M.B.,Stout, C.D.,Halpert, J.R. (deposition date: 2015-10-08, release date: 2016-02-10, Last modification date: 2023-09-27)
Primary citation	Shah, M.B.,Liu, J.,Huo, L.,Zhang, Q.,Dearing, M.D.,Wilderman, P.R.,Szklarz, G.D.,Stout, C.D.,Halpert, J.R. Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism. Mol.Pharmacol., 89:435-445, 2016 Cited by PubMed: 26826176 DOI: 10.1124/mol.115.102111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation