5E41

Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(N-(10-hydroxydecanoyl)-aminopentenyl)-2'-deoxyuridine-triphosphate

Summary for 5E41

• Entry DOI: 10.2210/pdb5e41/pdb
• Descriptor: DNA polymerase I, thermostable, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (7 entities in total)
• Functional Keywords: linker-modified nucleotide, klentaq, dna polymerase, transferase
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 3
• Total formula weight: 70641.06

Authors

Hottin, A.,Betz, K.,Marx, A. (deposition date: 2015-10-05, release date: 2016-12-07, Last modification date: 2024-01-10)

• Primary citation: Hottin, A.,Betz, K.,Diederichs, K.,Marx, A.; Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.; Chemistry, 23:2109-2118, 2017; PubMed: 27901305; DOI: 10.1002/chem.201604515

Experimental method

X-RAY DIFFRACTION (1.8 Å)