5E2Y

Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/duck/Egypt/10185SS/2010 (H5N1)

Summary for 5E2Y

• Entry DOI: 10.2210/pdb5e2y/pdb
• Related: 5E2Z 5E30 5E32 5E34 5E35
• Descriptor: Hemagglutinin, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: h5n1 influenza virus, hemagglutinin, receptor binding specificity, transmission, glycan complex, viral protein
• Biological source: Influenza A virus (A/duck/Egypt/10185SS/2010(H5N1)); More
• Total number of polymer chains: 6
• Total formula weight: 178092.24

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2015-10-01, release date: 2015-12-02, Last modification date: 2023-09-27)

• Primary citation: Zhu, X.,Viswanathan, K.,Raman, R.,Yu, W.,Sasisekharan, R.,Wilson, I.A.; Structural Basis for a Switch in Receptor Binding Specificity of Two H5N1 Hemagglutinin Mutants.; Cell Rep, 13:1683-1691, 2015; PubMed: 26586437; DOI: 10.1016/j.celrep.2015.10.027

Experimental method

X-RAY DIFFRACTION (2.6 Å)