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5DYC

Crystal structure of the human BRPF1 bromodomain in complex with SEED6

Summary for 5DYC
Entry DOI10.2210/pdb5dyc/pdb
Related5C7N 5C85 5C87 5C89 5D7X 5DY7 5DYA
DescriptorPeregrin, NITRATE ION, 7-bromo-3,4-dihydroquinoxalin-2(1H)-one, ... (4 entities in total)
Functional Keywordsdna binding protein, bromodomain and phd finger-containing protein 1(brpf1), monocytic leukemia zinc-finger (moz), inhibitor, transcription
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : P55201
Total number of polymer chains1
Total formula weight13992.76
Authors
Zhu, J.,Caflisch, A. (deposition date: 2015-09-24, release date: 2016-05-25, Last modification date: 2024-01-10)
Primary citationZhu, J.,Caflisch, A.
Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59:5555-5561, 2016
Cited by
PubMed: 27167503
DOI: 10.1021/acs.jmedchem.6b00215
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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