5DU1
Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P21 space group.
Summary for 5DU1
| Entry DOI | 10.2210/pdb5du1/pdb |
| Descriptor | Mambalgin-1 (2 entities in total) |
| Functional Keywords | acid sensing ion channels, elapid venoms, analgesic polypeptide, toxin |
| Biological source | Dendroaspis polylepis polylepis (Black mamba) |
| Cellular location | Secreted : P0DKR6 |
| Total number of polymer chains | 4 |
| Total formula weight | 26298.58 |
| Authors | Stura, E.A.,Tepshi, L.,Mourier, G.,Kessler, P.,Servent, D. (deposition date: 2015-09-18, release date: 2015-12-30, Last modification date: 2024-01-10) |
| Primary citation | Mourier, G.,Salinas, M.,Kessler, P.,Stura, E.A.,Leblanc, M.,Tepshi, L.,Besson, T.,Diochot, S.,Baron, A.,Douguet, D.,Lingueglia, E.,Servent, D. Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291:2616-2629, 2016 Cited by PubMed: 26680001DOI: 10.1074/jbc.M115.702373 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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