5DQO
Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
Summary for 5DQO
Entry DOI | 10.2210/pdb5dqo/pdb |
Related | 3L9Q |
Descriptor | DNA primase large subunit, IRON/SULFUR CLUSTER (3 entities in total) |
Functional Keywords | iron-sulfur cluster, dna priming, replication |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 92030.36 |
Authors | Salay, L.E.,Thompson, M.K.,Chazin, W.J. (deposition date: 2015-09-15, release date: 2016-09-21, Last modification date: 2023-09-27) |
Primary citation | O'Brien, E.,Holt, M.E.,Thompson, M.K.,Salay, L.E.,Ehlinger, A.C.,Chazin, W.J.,Barton, J.K. The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport. Science, 355:-, 2017 Cited by PubMed: 28232525DOI: 10.1126/science.aag1789 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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