5DPR

Crystal structure of PLEKHM1 LIR-fused human LC3A_2-121

Summary for 5DPR

Entry DOI	10.2210/pdb5dpr/pdb
Related	3X0W 5DPS 5DPT 5DPW
Descriptor	Pleckstrin homology domain-containing family M member 1,Microtubule-associated proteins 1A/1B light chain 3A (2 entities in total)
Functional Keywords	autophagy; plekhm1; atg8; lc3; gabarap, chimeric protein, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	63728.42
Authors	Ravichandran, A.C.,Suzuki, H.,Dobson, R.C.J. (deposition date: 2015-09-14, release date: 2016-09-28, Last modification date: 2024-03-06)
Primary citation	Rogov, V.V.,Stolz, A.,Ravichandran, A.C.,Rios-Szwed, D.O.,Suzuki, H.,Kniss, A.,Lohr, F.,Wakatsuki, S.,Dotsch, V.,Dikic, I.,Dobson, R.C.,McEwan, D.G. Structural and functional analysis of the GABARAP interaction motif (GIM). EMBO Rep., 18:1382-1396, 2017 Cited by PubMed: 28655748 DOI: 10.15252/embr.201643587 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation