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5DO9

Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q

Summary for 5DO9
Entry DOI10.2210/pdb5do9/pdb
DescriptorGuanine nucleotide-binding protein G(q) subunit alpha, Regulator of G-protein signaling 8, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywordsgtp-binding protein alpha subunits, gq-g11, rgs proteins, protein binding
Biological sourceMus musculus (Mouse)
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Cellular locationNucleus : P21279
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P57771
Total number of polymer chains6
Total formula weight159555.84
Authors
Taylor, V.G.,Tesmer, J.J.G. (deposition date: 2015-09-10, release date: 2016-01-20, Last modification date: 2024-03-06)
Primary citationTaylor, V.G.,Bommarito, P.A.,Tesmer, J.J.
Structure of the Regulator of G Protein Signaling 8 (RGS8)-G alpha q Complex: MOLECULAR BASIS FOR G alpha SELECTIVITY.
J.Biol.Chem., 291:5138-5145, 2016
Cited by
PubMed: 26755720
DOI: 10.1074/jbc.M115.712075
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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