5DH8

Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction- G12A mutant in Zn2+

Summary for 5DH8

• Entry DOI: 10.2210/pdb5dh8/pdb
• Related: 5DH6 5DH7 5DI2 5DI4
• Descriptor: RNA (48-MER), 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', ZINC ION (3 entities in total)
• Functional Keywords: ribozyme, hammerhead, rna
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 22772.50

Authors

Mir, A.,Chen, J.,Neau, D.,Golden, B.L. (deposition date: 2015-08-29, release date: 2015-10-07, Last modification date: 2024-03-06)

• Primary citation: Mir, A.,Chen, J.,Robinson, K.,Lendy, E.,Goodman, J.,Neau, D.,Golden, B.L.; Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.; Biochemistry, 54:6369-6381, 2015; PubMed: 26398724; DOI: 10.1021/acs.biochem.5b00824

Experimental method

X-RAY DIFFRACTION (3.297 Å)