5DCP

Crystal structure of the human filamin B Ig-like domains 16-17

Summary for 5DCP

• Entry DOI: 10.2210/pdb5dcp/pdb
• Descriptor: Filamin-B (2 entities in total)
• Functional Keywords: cytoskeleton, adhesion, immunoglobulin-like, actin binding protein, structural protein
• Biological source: Homo sapiens (Human)
• Cellular location: Isoform 1: Cytoplasm, cell cortex. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Cytoplasm, cytoskeleton. Isoform 6: Cytoplasm, cytoskeleton: O75369
• Total number of polymer chains: 2
• Total formula weight: 37498.29

Authors

Seppala, J.,Pentikainen, U.,Ylanne, J. (deposition date: 2015-08-24, release date: 2016-08-24, Last modification date: 2024-01-10)

• Primary citation: Seppala, J.,Bernardi, R.C.,Haataja, T.J.K.,Hellman, M.,Pentikainen, O.T.,Schulten, K.,Permi, P.,Ylanne, J.,Pentikainen, U.; Skeletal Dysplasia Mutations Effect on Human Filamins' Structure and Mechanosensing.; Sci Rep, 7:4218-4218, 2017; PubMed: 28652603; DOI: 10.1038/s41598-017-04441-x

Experimental method

X-RAY DIFFRACTION (2.49 Å)