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5DAP

Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ

Summary for 5DAP
Entry DOI10.2210/pdb5dap/pdb
Related4NAO
DescriptorPhytanoyl-CoA dioxygenase family protein (AFU_orthologue AFUA_8G00230), NICKEL (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
Functional Keywordsantibiotics, biosynthesis, alkaloids, viridicatin, desaturase, epoxidase, fragmentation, oxidoreductase
Biological sourceEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Total number of polymer chains1
Total formula weight34183.65
Authors
Groll, M.,Braeuer, A. (deposition date: 2015-08-20, release date: 2015-11-25, Last modification date: 2024-01-10)
Primary citationBrauer, A.,Beck, P.,Hintermann, L.,Groll, M.
Structure of the Dioxygenase AsqJ: Mechanistic Insights into a One-Pot Multistep Quinolone Antibiotic Biosynthesis.
Angew.Chem.Int.Ed.Engl., 55:422-426, 2016
Cited by
PubMed: 26553478
DOI: 10.1002/anie.201507835
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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