5DAH

Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide

Summary for 5DAH

• Entry DOI: 10.2210/pdb5dah/pdb
• Related: 5DAG
• Descriptor: Protein AF-10, Histone H3 peptide, ZINC ION, ... (5 entities in total)
• Functional Keywords: phd finger, histone tail reader, epigenetics, h3k27 recognition, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 49277.41

Authors

Chen, S.,Patel, D.J. (deposition date: 2015-08-19, release date: 2015-10-21, Last modification date: 2024-03-06)

• Primary citation: Chen, S.,Yang, Z.,Wilkinson, A.W.,Deshpande, A.J.,Sidoli, S.,Krajewski, K.,Strahl, B.D.,Garcia, B.A.,Armstrong, S.A.,Patel, D.J.,Gozani, O.; The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.; Mol.Cell, 60:319-327, 2015; PubMed: 26439302; DOI: 10.1016/j.molcel.2015.08.019

Experimental method

X-RAY DIFFRACTION (2.611 Å)