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5D28

Complex of GM-CSF/IL-2 inhibition factor with Granulocyte-macrophage colony-stimulating factor

Summary for 5D28
Entry DOI10.2210/pdb5d28/pdb
Related5D22
DescriptorGM-CSF/IL-2 inhibition factor, Granulocyte-macrophage colony-stimulating factor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordssignaling protein, cytokine, host-pathogen interactions, immunology, viral protein
Biological sourceOrf virus (ORFV)
More
Total number of polymer chains4
Total formula weight87805.03
Authors
Felix, J.,Savvides, S.N. (deposition date: 2015-08-05, release date: 2016-11-16, Last modification date: 2024-01-10)
Primary citationFelix, J.,Kandiah, E.,De Munck, S.,Bloch, Y.,van Zundert, G.C.,Pauwels, K.,Dansercoer, A.,Novanska, K.,Read, R.J.,Bonvin, A.M.,Vergauwen, B.,Verstraete, K.,Gutsche, I.,Savvides, S.N.
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.
Nat Commun, 7:13228-13228, 2016
Cited by
PubMed: 27819269
DOI: 10.1038/ncomms13228
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.845 Å)
Structure validation

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