5CVD

Crystal structure of human NRMT1 in complex with alpha-N-dimethylated human CENP-A peptide

Summary for 5CVD

• Entry DOI: 10.2210/pdb5cvd/pdb
• Related: 5CVE
• Descriptor: N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-teminal peptide from Histone H3-like centromeric protein A, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: alpha-n-methyltransferase, histone methylation, sam-mtase, cenp-a, transferase-peptide complex, transferase/peptide
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q9BV86 P49450
• Total number of polymer chains: 4
• Total formula weight: 58232.42

Authors

Wu, R.,Li, H. (deposition date: 2015-07-26, release date: 2015-11-25, Last modification date: 2024-03-20)

• Primary citation: Wu, R.,Yue, Y.,Zheng, X.,Li, H.; Molecular basis for histone N-terminal methylation by NRMT1; Genes Dev., 29:2337-2342, 2015; PubMed: 26543159; DOI: 10.1101/gad.270926.115

Experimental method

X-RAY DIFFRACTION (1.3 Å)