5CGQ

Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand in the alpha-site and the product L-Tryptophan in the beta-site.

Summary for 5CGQ

• Entry DOI: 10.2210/pdb5cgq/pdb
• Related: 2CLI 2CLL 3PR2 4HN4 4HPJ 4HPX 4HT3 4XUG 4Y6G 4ZQC 5BW6
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total)
• Functional Keywords: lyase, carbon-oxygen lyase, tryptophan biosynthesis, salmonella typhimurium, f6f, inhibitor, allosteric enzyme, aromatic amino acid biosynthesis, pyridoxal phosphate, transferase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium; More
• Total number of polymer chains: 2
• Total formula weight: 73058.22

Authors

Hilario, E.,Caulkins, B.G.,Young, R.P.,Dunn, M.F.,Mueller, L.J.,Fan, L. (deposition date: 2015-07-09, release date: 2016-07-13, Last modification date: 2023-09-27)

• Primary citation: Hilario, E.,Caulkins, B.G.,Young, R.P.,Dunn, M.F.,Mueller, L.J.,Fan, L.; Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand and the product L-Tryptophan in the beta-site.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.18 Å)