5CBM
Crystal structure of PfA-M17 with virtual ligand inhibitor
Summary for 5CBM
| Entry DOI | 10.2210/pdb5cbm/pdb |
| Related | 3KQZ |
| Descriptor | M17 family aminopeptidase, CARBONATE ION, ZINC ION, ... (8 entities in total) |
| Functional Keywords | m17 leucyl-aminopeptidase, protease, inhibitor, hydroxamic acid, hydrolase |
| Biological source | Plasmodium falciparum Vietnam Oak-Knoll (FVO) |
| Total number of polymer chains | 12 |
| Total formula weight | 705396.14 |
| Authors | Ruggeri, C.,Drinkwater, N.,McGowan, S. (deposition date: 2015-07-01, release date: 2015-10-07, Last modification date: 2024-01-10) |
| Primary citation | Ruggeri, C.,Drinkwater, N.,Sivaraman, K.K.,Bamert, R.S.,McGowan, S.,Paiardini, A. Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening. Plos One, 10:e0138957-e0138957, 2015 Cited by PubMed: 26406322DOI: 10.1371/journal.pone.0138957 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report
