5C6D

Crystal structure of USP7 in complex with UHRF1

Summary for 5C6D

Entry DOI	10.2210/pdb5c6d/pdb
Descriptor	Ubiquitin carboxyl-terminal hydrolase 7, E3 ubiquitin-protein ligase UHRF1 (3 entities in total)
Functional Keywords	usp7, uhrf1, hydrolase-ligase complex, hydrolase/ligase
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus : Q93009 Q96T88
Total number of polymer chains	4
Total formula weight	81486.19
Authors	Zhang, Z.-M.,Song, J. (deposition date: 2015-06-22, release date: 2015-09-09, Last modification date: 2023-09-27)
Primary citation	Zhang, Z.M.,Rothbart, S.B.,Allison, D.F.,Cai, Q.,Harrison, J.S.,Li, L.,Wang, Y.,Strahl, B.D.,Wang, G.G.,Song, J. An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Rep, 12:1400-1406, 2015 Cited by PubMed: 26299963 DOI: 10.1016/j.celrep.2015.07.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.292 Å)

Structure validation