5BZW

Crystal Structure of PCDN-27B, an antibody from the PCDN family of HIV-1 antibodies

Summary for 5BZW

Entry DOI	10.2210/pdb5bzw/pdb
Related	5BZD
Descriptor	2B3 HIV Antibody light chain, 2B3 HIV Antibody heavy chain, SULFATE ION, ... (5 entities in total)
Functional Keywords	hiv, antibody, fab, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	49129.56
Authors	Garces, F.,WILSON, I.A. (deposition date: 2015-06-11, release date: 2016-05-25, Last modification date: 2023-09-27)
Primary citation	MacLeod, D.T.,Choi, N.M.,Briney, B.,Garces, F.,Ver, L.S.,Landais, E.,Murrell, B.,Wrin, T.,Kilembe, W.,Liang, C.H.,Ramos, A.,Bian, C.B.,Wickramasinghe, L.,Kong, L.,Eren, K.,Wu, C.Y.,Wong, C.H.,Kosakovsky Pond, S.L.,Wilson, I.A.,Burton, D.R.,Poignard, P. Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity, 44:1215-1226, 2016 Cited by PubMed: 27192579 DOI: 10.1016/j.immuni.2016.04.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation