5BXV
eIF4E complex
Summary for 5BXV
| Entry DOI | 10.2210/pdb5bxv/pdb |
| Descriptor | Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | complex, translation |
| Biological source | Mus musculus (Mouse) More |
| Total number of polymer chains | 4 |
| Total formula weight | 55420.06 |
| Authors | Sekiyama, N.,Arthanari, H.,Papdopoulos, E.,Rodriguez-Mias, R.A.,Wagner, G.,Leger-Abraham, M. (deposition date: 2015-06-09, release date: 2015-07-15, Last modification date: 2023-09-27) |
| Primary citation | Sekiyama, N.,Arthanari, H.,Papadopoulos, E.,Rodriguez-Mias, R.A.,Wagner, G.,Leger-Abraham, M. Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1. Proc.Natl.Acad.Sci.USA, 112:E4036-E4045, 2015 Cited by PubMed: 26170285DOI: 10.1073/pnas.1512118112 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
