5BXJ

Complex of the Fk1 domain mutant A19T of FKBP51 with 4-Nitrophenol

Summary for 5BXJ

• Entry DOI: 10.2210/pdb5bxj/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL (3 entities in total)
• Functional Keywords: cochaperone, fk506, 4-nitrophenol, isomerase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q13451
• Total number of polymer chains: 1
• Total formula weight: 14296.38

Authors

Wu, D.,Tao, X.,Chen, Z.,Han, J.,Jia, W.,Li, X.,Wang, Z.,He, Y.X. (deposition date: 2015-06-09, release date: 2016-05-25, Last modification date: 2024-03-20)

• Primary citation: Wu, D.,Tao, X.,Chen, Z.P.,Han, J.T.,Jia, W.J.,Zhu, N.,Li, X.,Wang, Z.,He, Y.X.; The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells; J. Hazard. Mater., 307:193-201, 2016; PubMed: 26780698; DOI: 10.1016/j.jhazmat.2015.12.045

Experimental method

X-RAY DIFFRACTION (1.24 Å)