5BTL

Crystal structure of a topoisomerase II complex

Summary for 5BTL

Entry DOI	10.2210/pdb5btl/pdb
Descriptor	DNA gyrase subunit A, DNA gyrase subunit B, DNA substrate 24-mer GGTCATGAATGACTATGCACGTAA, ... (7 entities in total)
Functional Keywords	protein-dna complex, topoisomerase ii, isomerase-dna complex, isomerase/dna
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More
Total number of polymer chains	8
Total formula weight	199306.86
Authors	Blower, T.R.,Williamson, B.H.,Kerns, R.J.,Berger, J.M. (deposition date: 2015-06-03, release date: 2016-03-02, Last modification date: 2023-11-15)
Primary citation	Blower, T.R.,Williamson, B.H.,Kerns, R.J.,Berger, J.M. Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113:1706-1713, 2016 Cited by PubMed: 26792525 DOI: 10.1073/pnas.1525047113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation