5BPB

Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form I

Summary for 5BPB

Entry DOI	10.2210/pdb5bpb/pdb
Descriptor	Frizzled-4, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	wnt signalling pathway, glycoprotein, g protein coupled receptor, receptor for norrin recognition, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	67705.76
Authors	Chang, T.-H.,Hsieh, F.-L.,Harlos, K.,Jones, E.Y. (deposition date: 2015-05-27, release date: 2015-07-01, Last modification date: 2024-01-10)
Primary citation	Chang, T.H.,Hsieh, F.L.,Zebisch, M.,Harlos, K.,Elegheert, J.,Jones, E.Y. Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. Elife, 4:e06554-, 2015 Cited by PubMed: 26158506 DOI: 10.7554/eLife.06554 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation