5BON

Crystal structure of human Nudt15 (MTH2)

Summary for 5BON

Entry DOI	10.2210/pdb5bon/pdb
Descriptor	Probable 8-oxo-dGTP diphosphatase NUDT15, MAGNESIUM ION (3 entities in total)
Functional Keywords	nudix, mth2, dimer, nudt15, magnesium, nucleotide, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	149857.78
Authors	Carter, M.,Jemth, A.-S.,Helleday, T.,Stenmark, P. (deposition date: 2015-05-27, release date: 2015-08-05, Last modification date: 2024-01-10)
Primary citation	Carter, M.,Jemth, A.S.,Hagenkort, A.,Page, B.D.,Gustafsson, R.,Griese, J.J.,Gad, H.,Valerie, N.C.,Desroses, M.,Bostrom, J.,Warpman Berglund, U.,Helleday, T.,Stenmark, P. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun, 6:7871-7871, 2015 Cited by PubMed: 26238318 DOI: 10.1038/ncomms8871 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.799 Å)

Structure validation