5BO4

Structure of SOCS2:Elongin C:Elongin B from DMSO-treated crystals

Summary for 5BO4

• Entry DOI: 10.2210/pdb5bo4/pdb
• Descriptor: Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ... (4 entities in total)
• Functional Keywords: signaling protein, ubiquitin ligase, suppressor of cytokine signalling
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q15370 Q15369
• Total number of polymer chains: 18
• Total formula weight: 253225.53

Authors

Gadd, M.S.,Bulatov, E.,Ciulli, A. (deposition date: 2015-05-27, release date: 2015-07-08, Last modification date: 2017-10-18)

• Primary citation: Gadd, M.S.,Bulatov, E.,Ciulli, A.; Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases.; Plos One, 10:e0131218-e0131218, 2015; PubMed: 26121586; DOI: 10.1371/journal.pone.0131218

Experimental method

X-RAY DIFFRACTION (2.9 Å)