5BNI

Porcine CD38 complexed with complexed with a covalent intermediate, ribo-F-ribose-5'-phosphate

Summary for 5BNI

• Entry DOI: 10.2210/pdb5bni/pdb
• Related: 5BNF
• Descriptor: Uncharacterized protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (3 entities in total)
• Functional Keywords: covalent complex, adp-ribosyl cyclase, cd38, calcium signalling, hydrolase
• Biological source: Sus scrofa (Pig)
• Total number of polymer chains: 2
• Total formula weight: 53407.43

Authors

Ting, K.Y.,Leung, C.F.P.,Graeff, R.M.,Lee, H.C.,Hao, Q.,Kotaka, M. (deposition date: 2015-05-26, release date: 2016-05-25)

• Primary citation: Ting, K.Y.,Leung, C.F.,Graeff, R.M.,Lee, H.C.,Hao, Q.,Kotaka, M.; Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity.; Protein Sci., 25:650-661, 2016; PubMed: 26660500; DOI: 10.1002/pro.2859

Experimental method

X-RAY DIFFRACTION (2.5 Å)