5BMM
Src in complex with DNA-templated macrocyclic inhibitor MC25b
Summary for 5BMM
Entry DOI | 10.2210/pdb5bmm/pdb |
Related PRD ID | PRD_002183 |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, macrocyclic inhibitor MC25b (3 entities in total) |
Functional Keywords | transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Gallus gallus (Chicken) More |
Cellular location | Cell membrane : P00523 |
Total number of polymer chains | 4 |
Total formula weight | 66934.84 |
Authors | Georghiou, G.,Guja, K.E.,Aleem, S.,Kleiner, R.E.,Liu, D.R.,Miller, W.T.,Garcia-Diaz, M.,Seeliger, M.A. (deposition date: 2015-05-22, release date: 2016-09-21, Last modification date: 2023-11-15) |
Primary citation | Aleem, S.U.,Georghiou, G.,Kleiner, R.E.,Guja, K.E.,Craddock, B.P.,Lyczek, A.,Chan, A.I.,Garcia-Diaz, M.,Miller, W.T.,Liu, D.R.,Seeliger, M.A. Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chem Biol, 23:1103-1112, 2016 Cited by PubMed: 27593110DOI: 10.1016/j.chembiol.2016.07.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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