5B2G

Crystal structure of human claudin-4 in complex with C-terminal fragment of Clostridium perfringens enterotoxin

Summary for 5B2G

• Entry DOI: 10.2210/pdb5b2g/pdb
• Related: 3X29
• Descriptor: Endolysin,Claudin-4, Heat-labile enterotoxin B chain (2 entities in total)
• Functional Keywords: membrane protein, complex, cell-free protein expression system
• Biological source: Enterobacteria phage T4; More
• Total number of polymer chains: 8
• Total formula weight: 221161.19

Authors

Shinoda, T.,Kimura-Someya, T.,Shirouzu, M.,Yokoyama, S. (deposition date: 2016-01-15, release date: 2016-10-05, Last modification date: 2023-11-15)

• Primary citation: Shinoda, T.,Shinya, N.,Ito, K.,Ohsawa, N.,Terada, T.,Hirata, K.,Kawano, Y.,Yamamoto, M.,Kimura-Someya, T.,Yokoyama, S.,Shirouzu, M.; Structural basis for disruption of claudin assembly in tight junctions by an enterotoxin; Sci Rep, 6:33632-33632, 2016; PubMed: 27647526; DOI: 10.1038/srep33632

Experimental method

X-RAY DIFFRACTION (3.5 Å)