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5AYX

Crystal structure of Human Quinolinate Phosphoribosyltransferase

Replaces:  3LAR
Summary for 5AYX
Entry DOI10.2210/pdb5ayx/pdb
DescriptorNicotinate-nucleotide pyrophosphorylase [carboxylating] (2 entities in total)
Functional Keywordsquinolinate phosphoribosyltransferase, nad biosynthesis, nadc, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total formula weight191680.03
Authors
Kang, G.B.,Kim, M.-K.,Im, Y.J.,Lee, J.H.,Youn, H.-S.,An, J.Y.,Lee, J.-G.,Fukuoka, S.-I.,Eom, S.H. (deposition date: 2015-09-14, release date: 2016-02-03, Last modification date: 2023-11-08)
Primary citationYoun, H.-S.,Kim, T.G.,Kim, M.-K.,Kang, G.B.,Kang, J.Y.,Lee, J.-G.,An, J.Y.,Park, K.R.,Lee, Y.,Im, Y.J.,Lee, J.H.,Eom, S.H.
Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis
Sci Rep, 6:19681-19681, 2016
Cited by
PubMed: 26805589
DOI: 10.1038/srep19681
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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