5APM

Multiple capsid-stabilizing protein-RNA and protein-protein interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis

Summary for 5APM

• Entry DOI: 10.2210/pdb5apm/pdb
• EMDB information: 3137
• Descriptor: VP1, VP3, VP0 (3 entities in total)
• Functional Keywords: virus, picornavirus, parechovirus, human parechovirus 3, hpev3, neonatal sepsis, cryoem, image processing, single particle analysis
• Biological source: HUMAN PARECHOVIRUS 3 (HPEV3); More
• Total number of polymer chains: 3
• Total formula weight: 77999.49

Authors

Shakeel, S.,Westerhuis, B.M.,Domanska, A.,Koning, R.I.,Matadeen, R.,Koster, A.J.,Bakker, A.Q.,Beaumont, T.,Wolthers, K.C.,Butcher, S.J. (deposition date: 2015-09-17, release date: 2016-07-27, Last modification date: 2019-12-18)

• Primary citation: Shakeel, S.,Westerhuis, B.M.,Domanska, A.,Koning, R.I.,Matadeen, R.,Koster, A.J.,Bakker, A.Q.,Beaumont, T.,Wolthers, K.C.,Butcher, S.J.; Multiple Capsid-Stabilizing Interactions Revealed in a High-Resolution Structure of an Emerging Picornavirus Causing Neonatal Sepsis; Nat.Commun., 7:11387-, 2016; PubMed: 27435188; DOI: 10.1038/NCOMMS11387

Experimental method

ELECTRON MICROSCOPY (4.3 Å)