5AIZ

The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T-cell development and leukemia

Summary for 5AIZ

Entry DOI	10.2210/pdb5aiz/pdb
Descriptor	ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1, UNKNOWN ATOM OR ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	zinc-binding protein, protein
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus speckle : Q9ULJ6
Total number of polymer chains	1
Total formula weight	14348.70
Authors	Cho, H.J.,Murai, M.,Chiang, M.,Cierpicki, T. (deposition date: 2015-02-18, release date: 2015-10-28, Last modification date: 2015-12-02)
Primary citation	Cho, H.J.,Chiang, M.,Cierpicki, T. The Pias-Like Coactivator Zmiz1 is a Direct and Selective Cofactor of Notch1 in T-Cell Development and Leukemia Immunity, 43:870-, 2015 Cited by PubMed: 26522984 DOI: 10.1016/J.IMMUNI.2015.10.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation