5AHO

Crystal structure of human 5' exonuclease Apollo

Replaces:  3ZDK

Summary for 5AHO

• Entry DOI: 10.2210/pdb5aho/pdb
• Related: 5AHR
• Descriptor: 5' EXONUCLEASE APOLLO, 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, ... (5 entities in total)
• Functional Keywords: hydrolase, dna repair metallo-beta-lactamase, dclre1b
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Chromosome, telomere: Q9H816
• Total number of polymer chains: 1
• Total formula weight: 38700.04

Authors

Allerston, C.K.,Vollmar, M.,Krojer, T.,Pike, A.C.W.,Newman, J.A.,Carpenter, E.,Quigley, A.,Mahajan, P.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,Gileadi, O. (deposition date: 2015-02-06, release date: 2015-02-18, Last modification date: 2018-01-24)

• Primary citation: Allerston, C.K.,Lee, S.Y.,Newman, J.A.,Schofield, C.J.,Mchugh, P.J.,Gileadi, O.; The Structures of the Snm1A and Snm1B/Apollo Nuclease Domains Reveal a Potential Basis for Their Distinct DNA Processing Activities.; Nucleic Acids Res., 43:11047-, 2015; PubMed: 26582912; DOI: 10.1093/NAR/GKV1256

Experimental method

X-RAY DIFFRACTION (2.16 Å)