5AGW

Bcl-2 alpha beta-1 complex

Summary for 5AGW

• Entry DOI: 10.2210/pdb5agw/pdb
• Related: 5AGX
• Descriptor: APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1, APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 11 (3 entities in total)
• Functional Keywords: bcl-2, foldamer, bim, apoptosis
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 44137.49

Authors

Smith, B.J.,F Lee, E.,Checco, J.W.,Gellman, S.H.,Fairlie, W.D. (deposition date: 2015-02-04, release date: 2015-09-09, Last modification date: 2023-11-15)

• Primary citation: Checco, J.W.,Lee, E.F.,Evangelista, M.,Sleebs, N.,Rodgers, K.,Pettikiriarachchi, A.,Kershaw, N.,Eddinger, G.A.,Belair, D.G.,Wilson, J.L.,Eller, C.H.,Raines, R.T.,Murphy, W.L.,Smith, B.J.,Gellman, S.H.,Fairlie, W.D.; Alpha Beta Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity on Living Cells; J.Am.Chem.Soc., 137:11365-, 2015; PubMed: 26317395; DOI: 10.1021/JACS.5B05896

Experimental method

X-RAY DIFFRACTION (2.695 Å)