5AGV
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
Summary for 5AGV
| Entry DOI | 10.2210/pdb5agv/pdb |
| Related | 5AGU 5AH2 5AH4 |
| Related PRD ID | PRD_002466 |
| Descriptor | DNA POLYMERASE III SUBUNIT BETA, CYCLOHEXYL GRISELIMYCIN, CALCIUM ION, ... (6 entities in total) |
| Functional Keywords | transferase-antibiotic complex, transferase, dnan, natural product, sliding clamp, transferase/antibiotic |
| Biological source | MYCOBACTERIUM TUBERCULOSIS H37RV More |
| Total number of polymer chains | 4 |
| Total formula weight | 88320.55 |
| Authors | Lukat, P.,Kling, A.,Heinz, D.W.,Mueller, R. (deposition date: 2015-02-03, release date: 2015-06-03, Last modification date: 2024-01-10) |
| Primary citation | Kling, A.,Lukat, P.,Almeida, D.V.,Bauer, A.,Fontaine, E.,Sordello, S.,Zaburannyi, N.,Herrmann, J.,Wenzel, S.C.,Konig, C.,Ammerman, N.C.,Barrio, M.B.,Borchers, K.,Bordon-Pallier, F.,Bronstrup, M.,Courtemanche, G.,Gerlitz, M.,Geslin, M.,Hammann, P.,Heinz, D.W.,Hoffmann, H.,Klieber, S.,Kohlmann, M.,Kurz, M.,Lair, C.,Matter, H.,Nuermberger, E.,Tyagi, S.,Fraisse, L.,Grosset, J.H.,Lagrange, S.,Muller, R. Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348:1106-, 2015 Cited by PubMed: 26045430DOI: 10.1126/SCIENCE.AAA4690 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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