5A6Z

Structure of the LecB lectin from Pseudomonas aeruginosa strain PA14 in complex with lewis a

Summary for 5A6Z

Entry DOI	10.2210/pdb5a6z/pdb
Related	5A6Q 5A6X 5A6Y 5A70
Descriptor	LECB, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-galactopyranose, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	sugar binding protein, lectin, lecb, lewis antigen
Biological source	PSEUDOMONAS AERUGINOSA
Total number of polymer chains	4
Total formula weight	50026.15
Authors	Sommer, R.,Wagner, S.,Varrot, A.,Khaledi, A.,Haussler, S.,Imberty, A.,Titz, A. (deposition date: 2015-07-02, release date: 2016-05-25, Last modification date: 2024-01-10)
Primary citation	Sommer, R.,Wagner, S.,Varrot, A.,Nycholat, C.M.,Khaledi, A.,Haussler, S.,Paulson, J.C.,Imberty, A.,Titz, A. The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery. Chem Sci, 7:4990-5001, 2016 Cited by PubMed: 30155149 DOI: 10.1039/c6sc00696e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation