5KCA

Crystal structure of the Cbln1 C1q domain trimer in complex with the amino-terminal domain (ATD) of iGluR Delta-2 (GluD2)

Summary for 5KCA

Entry DOI	10.2210/pdb5kca/pdb
Descriptor	Cerebellin-1,Cerebellin-1,Cerebellin-1,Glutamate receptor ionotropic, delta-2, CALCIUM ION (2 entities in total)
Functional Keywords	cerebellin, ionotropic glutamate receptor (iglur), neurotransmission, signaling protein
Biological source	Homo sapiens (Human) More
Cellular location	Cell membrane ; Multi-pass membrane protein : O43424
Total number of polymer chains	1
Total formula weight	97277.78
Authors	Elegheert, J.,Aricescu, A.R. (deposition date: 2016-06-05, release date: 2016-07-27, Last modification date: 2024-01-10)
Primary citation	Elegheert, J.,Kakegawa, W.,Clay, J.E.,Shanks, N.F.,Behiels, E.,Matsuda, K.,Kohda, K.,Miura, E.,Rossmann, M.,Mitakidis, N.,Motohashi, J.,Chang, V.T.,Siebold, C.,Greger, I.H.,Nakagawa, T.,Yuzaki, M.,Aricescu, A.R. Structural basis for integration of GluD receptors within synaptic organizer complexes. Science, 353:295-299, 2016 Cited by PubMed: 27418511 DOI: 10.1126/science.aae0104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation