5G0H

Crystal structure of Danio rerio HDAC6 CD2 in complex with (S)- trichostatin A

Summary for 5G0H

Entry DOI	10.2210/pdb5g0h/pdb
Related	5G0F 5G0G 5G0I 5G0J
Descriptor	HDAC6, S-Trichostatin A, POTASSIUM ION, ... (6 entities in total)
Functional Keywords	cell cycle, histone, histone deacetylase
Biological source	DANIO RERIO (ZEBRAFISH)
Total number of polymer chains	1
Total formula weight	88581.06
Authors	Miyake, Y.,Keusch, J.J.,Wang, L.,Saito, M.,Hess, D.,Wang, X.,Melancon, B.J.,Helquist, P.,Gut, H.,Matthias, P. (deposition date: 2016-03-18, release date: 2016-07-27, Last modification date: 2016-09-28)
Primary citation	Miyake, Y.,Keusch, J.J.,Wang, L.,Saito, M.,Hess, D.,Wang, X.,Melancon, B.J.,Helquist, P.,Gut, H.,Matthias, P. Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition Nat.Chem.Biol., 12:748-, 2016 Cited by PubMed: 27454931 DOI: 10.1038/NCHEMBIO.2140 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation