Summary for 5B6O
| Entry DOI | 10.2210/pdb5b6o/pdb |
| Related | 2duc |
| Descriptor | 3C-like proteinase (2 entities in total) |
| Functional Keywords | hydrolase, structural genomics, riken structural genomics/proteomics initiative, rsgi |
| Biological source | Human SARS coronavirus (SARS-CoV) |
| Cellular location | Papain-like proteinase: Host membrane; Multi-pass membrane protein. Non-structural protein 4: Host membrane; Multi-pass membrane protein. Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X7 |
| Total number of polymer chains | 2 |
| Total formula weight | 69871.91 |
| Authors | Wang, H.,Kim, Y.,Muramatsu, T.,Takemoto, C.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2016-05-31, release date: 2016-06-15, Last modification date: 2023-11-08) |
| Primary citation | Muramatsu, T.,Takemoto, C.,Kim, Y.T.,Wang, H.,Nishii, W.,Terada, T.,Shirouzu, M.,Yokoyama, S. SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity Proc. Natl. Acad. Sci. U.S.A., 113:12997-13002, 2016 Cited by PubMed: 27799534DOI: 10.1073/pnas.1601327113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.202 Å) |
Structure validation
Download full validation report
