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4ZYR

Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)

Summary for 4ZYR
Entry DOI10.2210/pdb4zyr/pdb
Related1PV7 2V8N 2Y5Y 4OAA
DescriptorLactose permease, 4-nitrophenyl alpha-D-galactopyranoside, nonyl beta-D-glucopyranoside (3 entities in total)
Functional Keywordsmembrane protein, transporter, alpha-helical, major facilitator superfamily (mfs), transport protein
Biological sourceEscherichia coli (strain K12)
Total number of polymer chains2
Total formula weight94793.70
Authors
Kumar, H.,Finer-Moore, J.S.,Kaback, H.R.,Stroud, R.M. (deposition date: 2015-05-22, release date: 2015-07-29, Last modification date: 2023-09-27)
Primary citationKumar, H.,Finer-Moore, J.S.,Kaback, H.R.,Stroud, R.M.
Structure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site.
Proc.Natl.Acad.Sci.USA, 112:9004-9009, 2015
Cited by
PubMed: 26157133
DOI: 10.1073/pnas.1509854112
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.312 Å)
Structure validation

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