4ZH1

Complement factor H in complex with the GM1 glycan

Summary for 4ZH1

• Entry DOI: 10.2210/pdb4zh1/pdb
• Descriptor: Complement C3, Complement factor H, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... (7 entities in total)
• Functional Keywords: lectin, ganglioside, innate immunity, glycans, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P01024 P08603
• Total number of polymer chains: 6
• Total formula weight: 153330.11

Authors

Blaum, B.S.,Stehle, T. (deposition date: 2015-04-24, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Blaum, B.S.,Frank, M.,Walker, R.C.,Neu, U.,Stehle, T.; Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations.; Glycobiology, 26:532-539, 2016; PubMed: 26715202; DOI: 10.1093/glycob/cwv170

Experimental method

X-RAY DIFFRACTION (2.24 Å)