4Z0G

Structure of the IMPDH from Ashbya gossypii bound to GMP

Summary for 4Z0G

• Entry DOI: 10.2210/pdb4z0g/pdb
• Related: 4XWU
• Descriptor: Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION, ... (5 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056); More
• Total number of polymer chains: 2
• Total formula weight: 90772.38

Authors

Buey, R.M.,de Pereda, J.M.,Revuelta, J.L. (deposition date: 2015-03-26, release date: 2015-11-25, Last modification date: 2024-01-10)

• Primary citation: Buey, R.M.,Ledesma-Amaro, R.,Velazquez-Campoy, A.,Balsera, M.,Chagoyen, M.,de Pereda, J.M.,Revuelta, J.L.; Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases.; Nat Commun, 6:8923-8923, 2015; PubMed: 26558346; DOI: 10.1038/ncomms9923

Experimental method

X-RAY DIFFRACTION (1.25 Å)