4YQX

Mouse IL-2 Bound to JES6-1 scFv Fragment

Summary for 4YQX

• Entry DOI: 10.2210/pdb4yqx/pdb
• Descriptor: JES6-1 VH domain, JES6-1 VL domain, Interleukin-2, ... (6 entities in total)
• Functional Keywords: chemokine, antibody, complex, cytokine-immune system complex, cytokine/immune system
• Biological source: Rattus norvegicus (Mouse); More
• Total number of polymer chains: 6
• Total formula weight: 83953.71

Authors

Spangler, J.B.,Luca, V.C.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-03-13, release date: 2015-07-01, Last modification date: 2023-09-27)

• Primary citation: Spangler, J.B.,Tomala, J.,Luca, V.C.,Jude, K.M.,Dong, S.,Ring, A.M.,Votavova, P.,Pepper, M.,Kovar, M.,Garcia, K.C.; Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.; Immunity, 42:815-825, 2015; PubMed: 25992858; DOI: 10.1016/j.immuni.2015.04.015

Experimental method

X-RAY DIFFRACTION (2.826 Å)