4YP1

Misting with CDA

Summary for 4YP1

• Entry DOI: 10.2210/pdb4yp1/pdb
• Related: 4M9Z 4YP2
• Descriptor: Stimulator of interferon genes protein, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide (3 entities in total)
• Functional Keywords: msting, cda, immune system
• Biological source: Mus musculus (Mouse)
• Cellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein: Q3TBT3
• Total number of polymer chains: 2
• Total formula weight: 48384.62

Authors

Chin, K.H.,Chen, C.K.,Tu, Z.I.,Chou, S.H. (deposition date: 2015-03-12, release date: 2015-10-07, Last modification date: 2024-03-20)

• Primary citation: Chin, K.H.,Liang, J.M.,Yang, J.G.,Shih, M.S.,Tu, Z.L.,Wang, Y.C.,Sun, X.H.,Hu, N.J.,Liang, Z.X.,Dow, J.M.,Ryan, R.P.,Chou, S.H.; Structural Insights into the Distinct Binding Mode of Cyclic Di-AMP with SaCpaA_RCK.; Biochemistry, 54:4936-4951, 2015; PubMed: 26171638; DOI: 10.1021/acs.biochem.5b00633

Experimental method

X-RAY DIFFRACTION (2.65 Å)