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4YLW

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound

Summary for 4YLW
Entry DOI10.2210/pdb4ylw/pdb
Related4LS0
DescriptorDihydroorotate dehydrogenase (quinone), mitochondrial, methyl (2Z)-cyano[3-(3-fluoro-4'-methoxybiphenyl-4-yl)-4-oxo-1,3-thiazolidin-2-ylidene]acetate, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
Functional Keywordsinhibitor, rheumatoid arthritis, complex, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion inner membrane ; Single-pass membrane protein : Q02127
Total number of polymer chains1
Total formula weight44607.89
Authors
Wu, D.,Ouyang, P.,Lu, W.,Huang, J. (deposition date: 2015-03-06, release date: 2016-03-09, Last modification date: 2023-11-08)
Primary citationWu, D.,Ouyang, P.,Lu, W.,Huang, J.
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.79 Å)
Structure validation

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