4YJV

THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250

Summary for 4YJV

Entry DOI	10.2210/pdb4yjv/pdb
Descriptor	Tyrosine-protein kinase SYK, 3-[6-({4-[ethyl(1H-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1H-indazol-1-yl]propan-1-ol (3 entities in total)
Functional Keywords	syk, non-receptor tyrosine kinase, spleen tyrosine kinase, transferase, phosphorylation, transferase-transferase inhibitor complex
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane : P43405
Total number of polymer chains	1
Total formula weight	33259.10
Authors	Somers, D.O.,Neu, M.,Stuckey, J. (deposition date: 2015-03-03, release date: 2015-10-14)
Primary citation	Somers, D.O.,Neu, M.,Stuckey, J. THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250 to be published,
Experimental method	X-RAY DIFFRACTION (1.652 Å)

Structure validation